Biologics - 24 Pages

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Biologics

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Over 1 million times per year, Biomet helps one surgeon provide personalized care to one patient. The science and art of medical care is to provide the right solution for each individual patient. This requires clinical mastery, a human connection between the surgeon and the patient, and the right tools for each situation. At Biomet, we strive to view our work through the eyes of one surgeon and one patient. We treat every solution we provide as if it’s meant for a family member. Our approach to innovation creates real solutions that assist each surgeon in the delivery of durable...

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Our Philosophy The Biomet Biologics Product Portfolio represents the passionate pursuit of the most innovative and clinically relevant solutions addressing the needs of surgeons and their patients. As a leader in autologous products, Biomet Biologics offers a myriad of solutions for both hard and soft tissue applications, including bone grafting products, StaGraft DBM Putty & PLUS platelet and plasma concentration systems, a B BMA (blood and bone marrow aspirate) concentration StaGraft Canc. DBM Sponge/Strips system, an autologous activation system and bone marrow aspiration needles. Also...

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CERAMENT™|BONE VOID FILLER Bonus Synthetic Bone Graft Substitute

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Osteoconductive Materials Osteoconductive materials provide the framework or scaffolding within a bony environment for cells to infiltrate and attach. They also offer porosity for vascular pathways and cell migration. Materials generally referred to as osteoconductive include certain calcium phosphate/ calcium sulfate based synthetics and allograft cortical as well as cancellous chips, sponges, and strips.1, 2 Although autograft is considered the gold standard for orthopedic procedures requiring graft material, it has known limitations with associated donor site morbidity and limited...

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CERAMENT ™|BONE VOID FILLER CERAMENT™|BONE VOID FILLER is an injectable synthetic bone graft substitute combining two materials – calcium sulfate and hydroxyapatite – with a radiopacity enhancing agent, in a 40% hydroxyapatite, 60% calcium sulfate ratio. • Injectable: Allows the material to be injected into cavities or drill holes through narrow gauge needles or delivery systems4, 6 • Biphasic: The calcium sulfate is gradually resorbed during months, allowing for natural bone ingrowth while the hydroxyapatite acts as a long-term scaffold embedded into the new bone5 • Osteoconductive:...

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Osteoconductive Materials Bonus Synthetic (Pro Osteon 500R) Bone Graft Substitute Bonus Synthetic Bone Graft Substitute granules are resorbable, osteoconductive matrices consisting of a thin, 2–10 micron layer of hydroxyapatite over a calcium carbonate core. Bonus Synthetic Bone Graft Substitute has been indicated as a bone graft substitute that resorbs and is replaced with bone during the healing process. Its interconnected porosity, chemical composition, and 6–18 month resorption time makes Bonus Synthetic an environment for new bone growth. 8 • Structure and porosity mimics human...

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Osteoinductive Materials Osteoinductive materials induce bone formation in a bony or non-bony environment via the action of growth factors or signaling proteins, including Bone Morphogenetic Proteins (BMPs). These proteins stimulate the conversion of progenitor cells into bone forming osteoblasts.2, 9 Materials that are generally referred to as osteoinductive in nature include demineralized bone matrix (DBM) and BMP products. Biomet Biologics products that fit this category include: StaGraft DBM products (Putty, PLUS,* Cancellous DBM Sponge and Strips), Bonus CC Matrix Bone Graft System,...

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StaGraft Cancellous DBM Sponge and Strips The StaGraft Cancellous DBM sponge and strips are machined from a single piece of cancellous bone. The cancellous bone is demineralized, exposing the inherent growth factors that are essential for new bone formation. Rehydration can be achieved with blood, bone marrow aspirate (BMA), or saline solution. The demineralization process and trabecular structure provide sponge-like handling, which allows the grafts to fit into a variety of bone voids or spinal cavities. If compressed, these products will expand to fill the contours of a void, thereby...

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Osteoinductive Materials StaGraft DBM Putty and PLUS StaGraft DBM is an osteoinductive demineralized bone matrix in a natural lecithin carrier, and is available as a 40% DBM Putty, or 35% DBM PLUS pre-mixed with resorbable coralline hydroxyapatite granules/calcium carbonate granules. The natural quality of the carrier and its outstanding containment and handling characteristics enable the surgeon to mold it to surgical sites, even in the presence of excessive fluids and under lavage. • Excellent handling and performance characteristics – tolerates lavage/irrigation • DBM-to-carrier ratio...

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Bonus CC Matrix Bone Graft System Bonus CC Matrix Bone Graft System is a unique formulation of cortical and cancellous bone which provides an osteoconductive scaffold for bone growth with flexible hydrating and handling options. Bonus CC Matrix offers all the benefits of allograft DBM while providing a consistent and efficient method of hydration. Bonus CC Matrix Bone Graft System is a 50/50 mixture of demineralized human cortical bone and mineralized ground cancellous bone derived from a single donor. The versatile delivery syringe allows Bonus CC Matrix to be hydrated with a carrier of...

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Osteopromotive Materials Osteopromotive* materials enhance the natural bone healing process.10–12 PRP is mixed with autograft or allograft materials to impart better graft-handling characteristics.10 Biomet Biologics products that fit this category include the GPS III Platelet Concentration System, BioCUE Blood and Bone Marrow Aspirate (B BMA) Concentration System, Plasmax Plasma Concentration System, and Clotalyst Autologous Activation System. *Products that produce a PRP output do not currently have FDA clearance to be characterized with a specific mechanism of action. PRP, in and of...

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