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HB-100

HB-100

HB-100

Product catalog summary
About Zivak Technologies
Zivak Technologies is a global company specializing in providing ready-to-use LC-MS/MS and HPLC analysis kits for clinical diagnostics. They offer fully automated systems for sample preparation and injection, enhancing the efficiency and speed of chromatography instruments.
The Role of HbA1c in Clinical Analysis
HbA1c is a critical parameter for diabetes screening and monitoring, formed by the combination of hemoglobin and sugar in the blood. Its levels rise with increased blood sugar, making it a direct indicator of high blood glucose. The analysis involves separating HbA1c from other species using a cation exchange column and pH gradient.
The Role of Hemoglobin Variants in Clinical Analysis
Hemoglobin variants are abnormal forms of hemoglobin resulting from genetic changes. Common variants include Hb E, Hb C, and Hb S, each associated with specific conditions like thalassemia and sickle cell disease. Analysis involves separating these variants using similar methods as HbA1c.
Methods for Analysis
Two main analytical concepts exist: separation of Hb fractions and chemical reactions. Techniques like ion exchange chromatography, capillary electrophoresis, and affinity chromatography are used for separation, while chemical tests involve specific reactions to measure HbA1c concentration. Each method has its strengths and limitations regarding throughput, quality, and detection of variants.
HB-100 Analyzer
The HB-100 Analyzer by Zivak Technologies automates the entire process from sample preparation to result transfer, minimizing errors and contamination risks. It features robotic arms for sample handling, barcode reading, and automated data processing with the AutoMass HB-100 Software.
Chromatograms
The document includes sample chromatograms for HbA1c and Hb variants, illustrating retention times and absorbance levels for various hemoglobin components.
HB-100 Specifications
The HB-100 system operates at 220-230V AC, with a sample capacity of 110 samples and analysis times of 1.5 minutes for HbA1c and 6.5 minutes for variants. It includes features like a barcode reader, shaker module, and specialized detector for HbA1c and variant analysis.
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Catalog excerpts

HB-100-1

x.iVAK TECHNOLOGIES GOLD STANDARD ACCURACY By Ion-Exchange HbAlc and Hb Variants

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HB-100-2

ZiVAtC TECHNOLOGIES UNIQUE SOLUTION FROM ONE COMPANY Zivak Technologies is an international special company providing ready to use LC-MS/MS and HPLC analysis kits in the clinical diagnostic field. The Research&Development company also supplies its own fully automated sample preparation and injection systems which enables laboratories around the globe to make efficient use of their chromatography instruments as well as their employees in a fast, accurate and cost efficient way. © The role of HbA1c in Clinical Analysis? © The role of Hemoglobin Variants in Clinical Analysis? What are the Methods?...

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HB-100-3

The role of HbA1c in Clinical Analysis The amount of HbA1c in whole blood is one of the most important parameters for diabetes screening and monitoring. HbA1c is formed by combination of hemoglobin protein and sugar in the blood. The production of HbA1c rises when the rate of blood sugar increases. Therefore, the amount of HbA1c is directly related with high blood glucose. The different types of HbA1c molecules can be occurred such as A1a, A1b, s-A1c, L-A1c, according to the type of sugar which combined to the hemoglobin. The most important part of the HbA1c analysis is the best separation of...

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HB-100-4

ZiVAtC TECHNOLOGIES What are the Methods? The relevance of the HbA1c concentration in diabetes management is well recognized by the diagnostic industry, and various commercial tests have been developed in this respect. There are two major analytical concepts: one, based on the separation of Hb fractions and the other, based on chemical reactions. The fact that HbA1c and non-glycated Hb have different chemical properties allows for the separation of fractions and the quantification of HbA1c. This principle is applied in ion exchange chromatography (IEC), capillary electrophoresis (CE), and affinity...

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HB-100-5

ZiVAK TECHNOLOGIES HB-100: Direct LIS transfer from beginning to end Zivak Technologies has developed state of the art Hemoglobin A1c and Variant Analyzer. This eliminates the errors from manual sample preparation steps. With HB-100 Hemoglobin A1c and Variant Analyzer, the low throughput in chromatography analysis will not be a problem for the laboratories any more. Zivak HB-100 system can inject from closed cap whole blood collection tubes. This eliminates the contamination risk from the opening tubes for the technician. All sample preparation steps for analysis made by the unique modules of...

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HB-100-6

HB-100: HbA1c Chromatogram Sample Chromatogram HbAo 1.347 HB-100: Hb-Variants Chromatogram Sample Chromatogram Hb Variant chromatogram Zivak Technologies Retention time

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HB-100-7

ZiVAK TECHNOLOGIES HB-100: SPECIFICATIONS TECHNICAL SPECIFICATIONS GENERAL ® Power Requirements: - Operating Voltage: 220-230V AC - Operating Frequency: 50 - 60 Hz - Operating Current: 5,95A Max ® Dimensions(W x D x H): 766mm x 714mm x 757mm ® Working Temperature: 10 - 40 oC ® Storage Temperature: -20 - 70 oC ® Humidity: %30 - 80 RH Sound Level: < 60dB @1m SAMPLING & INJECTION ©Sample Capacity: 110 (2 mL VacuTube) samples with continuous loading ® Loop Volume: 20 uL ©Analysis time: HbA1c 1,5 Min. Variant 6,5 Min. ©Syringe volume: Standart sizes 50 uL, 10 mL Wash Solvent: External wash solvent...

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HB-100-8

FUTURE OF ANALYSIS www.zivak.com Katalogda yer alan tüm ürünlerin TİTUBB kayıtları, T.C. Sağlık Bakanlığı Türkiye İlaç ve Tıbbi Cihaz Kurumu yönetmeliklerine ve genelgelerine uygun olarak gerçekl

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