DFC-620SP
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DFC-620SP - 1

PHARMA • TEST DFC-620SP - Semi-Automated Dissolution Test System The offline DFC systems include a fraction collector or an auto sampler which will collect the sampled dissolution media. The semi-automated DFC-620SP system is composed of a PTWS 620 staggered stirrer start dissolution bath with built-in individual vessel centering, full tubing installation in PTFE including either in-situ sampling probes or the EPE-620 auto sampling system, a PT-SP8 syringe pump, and a PTFC-2/8 fraction collector. In this configuration the sampling probes are either always immersed into the media (in-situ) or removed after sampling (EPE-620 system). Both procedures are widely used. For more details on the PTWS 620 dissolution bath, the PT-SP and the PTFC-2/8 fraction collector download the individual instrument brochures from www.pharma-test.com. Pharma Test Apparatebau AG P: +49 6182 9532 600

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DFC-620SP - 2

DFC-620SP - Semi-Automated Dissolution Test System What Does Semi Automated Tablet Dissolution Testing Mean? Semi-automated in this case means auto sampling for a dissolution test instrument at pre-programmed times. Automating this step alone eases the dissolution job a lot. After all tablets have been dropped, the dissolution test proceeds automatically and all samples are simultaneously removed from each connected vessel. The sample is delivered into a connected fraction collector by a peristaltic-, or the PT-SP syringe pump. These systems do not require any external PC software to...

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DFC-620SP - 3

DFC-620SP - Semi-Automated Dissolution Test System peristaltic pumps available today has vastly improved, it must be stressed that the peristaltic pump is still working with flexible tubing and should be qualified at the start of each determination to make sure that the flow rates are identical for each channel and that the tubing itself is in overall good condition. A good tip for long tubing life is to always release the pressure rollers from the tubing either overnight or whenever the system is left for extended periods of time and not in use. The PT-SP multi-syringe pump is designed...

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DFC-620SP - 4

DFC-620SP - Semi-Automated Dissolution Test System

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DFC-620SP - 5

DFC-620SP - Semi-Automated Dissolution Test System Operation Principle As soon as the samples have been inserted, the system will start its automated operation. The sampling times have been programmed via the touch screen of the PTWS 620 dissolution bath and are saved as a specific method for subsequent tests. After the start of test a command is sent from the dissolution bath to the PTFC-2/8 fraction collector and from there to the connected pump to start a sampling sequence. The EPE-620 moves the sampling tubes and filter tips into the media to the selected sampling position. The pump...

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DFC-620SP - 6

DFC-620SP - Semi-Automated Dissolution Test System Standard Scope of Supply The DFC-620SP system comes ready to use with the following standard scope of supply: ■ TM-620 manual tablet drop magazine ■ EPE-620 automated sampling system ■ PTFE tubing installation for offline sampling ■ PTFC 2/8 fraction collector (sampling only) ■ PT-SP8 syringe pump ■ One set of stainless steel paddles ■ One set of 1000ml Borosilicate glass vessels ■ One set of depth adjustment balls ■ One bottle of ALGEX water preservative ■ Comprehensive documentation folder including: ■ User manual ■ DQ/QC instrument...

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