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Ion S5 and Ion S5 XL Systems. Targeted sequencing has never been simpler.

Ion S5 and Ion S5 XL Systems. Targeted sequencing has never been simpler.
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Ion S5 and Ion S5 XL Systems Targeted sequencing has never been simpler

Explore the Ion S5 and Ion S5 XL Systems Adopting next-generation sequencing (NGS) in your lab is now simpler than ever The Ion S5™ and Ion S5™ XL Systems provide the simplest DNA-to-data workﬂow for targeted sequencing with industry-leading speed and affordability. This allows you to spend less time doing repetitive lab work, and more time answering the critical questions in your research. Want to sequence small gene panels or bacterial genomes on Monday, and exomes or transcriptomes on Wednesday? Ion S5 and Ion S5 XL Systems let you leverage a single benchtop instrument that scales to...

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Ion S5 and Ion S5 XL Systems. Targeted sequencing has never been simpler. - 4

“That’s it? That’s all I have to do? This is really easy to set up.” Susana Häggqvist Research Engineer Uppsala Genome Center, Swe

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Ion S5 and Ion S5 XL Systems. Targeted sequencing has never been simpler. - 5

Simplicity Ready. Set. Sequence. The Ion S5 and Ion S5 XL Systems come with load-and-go reagents and a straightforward user interface, so you can set up the sequencer in less than 15 minutes of hands-on time. You can also track your consumables with ease and accuracy with the automated radio frequency identiﬁcation (RFID) tracking feature of the systems. By adding an Ion Chef™ System to your lab, you can beneﬁt from automated library and template preparation, so you can go from DNA to data in less than 45 minutes of total hands-on time. Cartridge-based reagents Less than 15 minutes of...

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Ion S5 and Ion S5 XL Systems. Targeted sequencing has never been simpler. - 6

Scalability Single sequencer. Multiple applications. Focus your efforts on applications that have the potential to be impactful. Each Ion S5 and Ion S5 XL System currently supports four different chip types that scale to various levels of sample throughput, enabling a wide range of research applications. Select from various Ion chips for a throughput range of 2 to 80 million reads per run using just one instrument. This ﬂexibility also means reduced need for sample batching to achieve optimum cost efﬁciency. Just select the chip type that matches your speciﬁc throughput or application...

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Ion S5 and Ion S5 XL Systems. Targeted sequencing has never been simpler. - 7

Choosing the right chip type for your throughput and application Example of our popular panels and applications Panel description Ion AmpliSeq Cancer Hotspot Panel v2 Identify cancer hotspot SNVs from 10 ng of FFPE DNA Ion Torrent Oncomine Focus Assay Identify solid tumor–relevant SNVs, indels, CNVs, and gene fusions from 52 genes, with a single workﬂow using FFPE samples Ion Torrent Oncomine Comprehensive Assay v3 Enable biomarker discovery of SNVs and indels and full gene sequencing from 161 genes, with a single workﬂow using FFPE samples Ion Torrent™ Oncomine™ Lung cfDNA Assay Detect...

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Ion S5 and Ion S5 XL Systems. Targeted sequencing has never been simpler. - 8

Speed Because every hour counts. A few hours could make all the difference in your quest for the right answer. Unlike light-based sequencers, there are no cumbersome optics or labeled nucleotides with semiconductor sequencing technology. The Ion S5 Systems are the only benchtop NGS platforms with run times as short as 2.5 hours, and rapid DNA-to-data workﬂows that can be completed in as little as 24 hours. Sequencing run times of 2.5–4 hours DNA to data in as little as 24 hour

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Ion S5 and Ion S5 XL Systems. Targeted sequencing has never been simpler. - 9

Small sample input Because every sample matters. Explore complex pathways with your low-input or degraded samples with Ion AmpliSeq™ technology, which enables you to prepare libraries from just a few nanograms of low-quality DNA or RNA. Cited by hundreds of publications in just four years— you can count on this highly referenced technology for consistent and robust library preparation. As little as 1 ng of DNA or RNA For low-quality, low-input samples

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Ion S5 and Ion S5 XL Systems. Targeted sequencing has never been simpler. - 10

Simple data analysis and storage Go from data to variants in a few clicks. Whether you are new to NGS or an experienced user, Torrent Suite™ Software and Ion Reporter™ Software make it easy for you to get started with NGS. Primary analysis: Torrent Suite Software • Easily plan, monitor, track, and analyze your runs using the webbased interface • Conduct raw data analysis, alignment, and variant calling with optimized plug-ins Secondary analysis: Ion Reporter Software • Integrate, annotate, and interpret variants • Cloud or on-site options available to meet your needs Data storage • Securely...

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Ion S5 and Ion S5 XL Systems. Targeted sequencing has never been simpler. - 11

Ion S5 Systems Simple, scalable, and rapid workﬂow for panels, microbes, exomes, and transcriptomes Ion S5 System Analysis time** Long-read sequencing for research applications such as human leukocyte antigen (HLA) typing or metagenomic analysis Ion S5 System Analysis time** * Expected output with >99% aligned or measured accuracy. Output dependent on read length and application. ** Analysis time to aligned BAM ﬁles. † Ion 510 Chip is only compatible with the Ion Chef System workﬂow for template preparation. The Ion 510 Chip is not enabled for the Io

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Ion S5 and Ion S5 XL Systems. Targeted sequencing has never been simpler. - 12

Service and support We are here to help. With more than 3,700 global sales, service, and technical support specialists available to assist you in person, by phone, or online, you can be conﬁdent that we will be there when and where you need us most. We invite you to start sequencing with the Ion S5 and Ion S5 XL Systems, based on technology adopted by your peers and supported by our scientists. Europe 60 ﬁeld application specialists, 103 ﬁeld service engineers Americas 90 ﬁeld application specialists, 120 ﬁeld service engineers Asia Paciﬁc 22 ﬁeld application specialists, 33 ﬁeld service...

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