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PaxScan® CBCT Software Tools Cone Beam CT Tool Kit Product Description Varex Imaging is a leading supplier of CBCT-enabling flat panel detectors and X-ray tubes, and is now providing companion image processing algorithms and CBCT reconstruction in the form of an easy to use software toolkit: CBCT Software Tools, or CST for short. CST is designed for use with all Varex Imaging X-Ray fluoroscopic flat panel detectors. It comprises a suite of Windows-based software libraries that enables OEMs to quickly develop software that produces high- quality 2D images or 3D reconstructions for medical, dental, or industrial applications. Within CST, individual processing steps are encapsulated into separate plugins. A host application can use any or all of the plugins provided. At the heart of CST is the Reconstruction Pipeline library. This library manages the available plugins and acts as the single interface between an OEM host application and the CST plugins. Key features of the Reconstruction Pipeline library: • Has a stable, easy to use API supporting both .NET and C++ host applications • Supports different panels, geometries, and scan types • Supports simultaneous acquisition and reconstruction processing Available plugins for CST include: • Scatter Correction – This pre-processing step corrects for the effects of scatter of the beam as it passes through the object (and any table or platform) being scanned. • Beam Hardening Correction – This pre-processing step corrects for the effects of hardening of the X-ray spectrum as the beam passes through the object. • Lag Correction – This pre-processing step corrects for the lag, or residual signal on the detector, from one frame to the next. • Resolution Enhancement (REA) – This pre-processing step removes the impact of the scintillator light spread to approach the limiting pixel resolution of the detector. • Normalization – This pre-processing step normalizes the input data based on a previous air calibration scan, and optionally supports position-dependent air calibration. • FDK Reconstruction – This step transforms a set of 2D projection frames into a reconstructed 3D volume. CST is delivered with two separate plugins to perform our modified implementation of FDK. The first is highly optimized for multicore CPUs. The second is designed to work with an NVIDIA GPU to further reduce computation time, and also supports 12-DOF dynamic wobble. • Ring Correction – This post-processing step corrects for ring artifacts, caused by small gain linearity differences between adjacent detectors • Hounsfield Unit Adjustments – This post-processing step converts the output image to Hounsfield units. • Customer-developed Plugins – CST provides the tools for OEMs to write their own custom processing steps, to either replace a CST-provided plugin or to provide additional processing.

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PaxScan® CBCT Software Tools Cone Beam CT Tool Kit Figure 1 - Pelvic phantom; no advanced corrections Figure 2 - All CST-provided corrections applied and rotation axis, and also supports 12-DOF dynamic geometry to measure gantry wobble. This information is then used by the CST plugins during reconstruction. IsoCal is an optional feature, and system geometry can also be explicitly specified to the CST pipeline directly by the OEM. The two figures above show the same slice from a reconstructed image of a pelvic phantom (both are displayed using the same window/level values). In Figure 1, no...

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